Content last updated on: May 29, 2017


A summary of TRAPS

TRAPS is an abbreviation of TNF-receptor associated periodic syndrome. It is a rare disease characterized by recurrent episodes with fever and other inflammatory symptoms. The disease is caused by changes in the TNFR1-gene. TRAPS is treated with anti-inflammatory drugs.


Fever is a major symptom in TRAPS

Patients with TRAPS suffer from recurrent episodes (attacks) of spiking fever. These attacks can last several weeks, but shorter attacks can be present. The length of an attack varies between patients and between attacks.

Other symptoms of TRAPS are:

- fatigue

- red eyes

- swollen eyelids

- abdominal pain and nausea

- headache

- testicular pain in men.

Symptoms disappear spontaneously at the end of an attack. It can take several days for the symptoms to completely recover. The severity of the symptoms varies between attacks. When several attacks present in a short time, the body has less time to recover from the attacks. Fatigue can last longer in this situation. In between the attacks, a patient with TRAPS feels generally healthy. The frequency of the attack is variable. A majority of patients has approximately 2 attacks each year, but more frequent attacks can be present.


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